Dulaglutide

Also known as: Trulicity

Weight LossFDA APPROVED

Clinical Status

FDA Approved — Type 2 diabetes, cardiovascular risk reduction.

Mechanism of Action

GLP-1 receptor agonist fused to a modified IgG4 Fc fragment for extended half-life. Activates GLP-1 receptors to enhance insulin secretion, suppress glucagon, and slow gastric emptying.

Dosing Defaults

Dose

0.75-4.5 mg weekly

Frequency

Once weekly

Administration

Subcutaneous injection

Timing

Same day each week

Food

with or without

Duration

Long-term use

Dose range: 0.75-4.5 mg weekly

Weekly injection — consistency of day matters more than time.

Side Effects

•Nausea
•Diarrhea
•Vomiting
•Abdominal pain
•Decreased appetite
•Fatigue
•Pancreatitis

Contraindications & Warnings

⚠Personal/family history of medullary thyroid carcinoma
⚠MEN 2 syndrome

•Not medical advice
•BOXED WARNING: Thyroid C-cell tumors

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This information is for educational purposes only and is not medical advice. Dosing data is based on research literature and community reports. Always consult a qualified healthcare provider before using any peptide.