Tirzepatide
Also known as: Mounjaro, Zepbound
Clinical Status
FDA Approved — Type 2 diabetes, chronic weight management.
Mechanism of Action
Activates both GLP-1 and GIP receptors, providing synergistic effects on appetite suppression, insulin secretion, and metabolic regulation.
Dosing Defaults
Dose
5-15 mg weekly
Frequency
Once weekly
Administration
Subcutaneous injection weekly
Timing
Morning, same day each week
Food
with or without
Duration
Long-term / chronic use
Dose range: 2.5-15 mg weekly
Weekly injection — consistency of day matters more than time of day.
Side Effects
- •Nausea
- •Diarrhea
- •Vomiting
- •Constipation
- •Decreased appetite
- •Abdominal pain
- •Pancreatitis
- •Gallbladder problems
Contraindications & Warnings
- ⚠Personal/family history of medullary thyroid carcinoma
- ⚠MEN 2 syndrome
- •Not medical advice
- •BOXED WARNING: Thyroid C-cell tumors
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This information is for educational purposes only and is not medical advice. Dosing data is based on research literature and community reports. Always consult a qualified healthcare provider before using any peptide.