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Tirzepatide

Also known as: Mounjaro, Zepbound

Weight LossFDA APPROVED

Clinical Status

FDA Approved — Type 2 diabetes, chronic weight management.

Mechanism of Action

Activates both GLP-1 and GIP receptors, providing synergistic effects on appetite suppression, insulin secretion, and metabolic regulation.

Dosing Defaults

Dose

5-15 mg weekly

Frequency

Once weekly

Administration

Subcutaneous injection weekly

Timing

Morning, same day each week

Food

with or without

Duration

Long-term / chronic use

Dose range: 2.5-15 mg weekly

Weekly injection — consistency of day matters more than time of day.

Side Effects

  • Nausea
  • Diarrhea
  • Vomiting
  • Constipation
  • Decreased appetite
  • Abdominal pain
  • Pancreatitis
  • Gallbladder problems

Contraindications & Warnings

  • Personal/family history of medullary thyroid carcinoma
  • MEN 2 syndrome
  • Not medical advice
  • BOXED WARNING: Thyroid C-cell tumors

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Use the reconstitution calculator to prepare your Tirzepatide dose.

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This information is for educational purposes only and is not medical advice. Dosing data is based on research literature and community reports. Always consult a qualified healthcare provider before using any peptide.